IFN-γ Directly Controls IL-33 Protein Level through a STAT1- and LMP2-dependent Mechanism

IL-33 contributes to disease processes in association with Th1 and Th2 phenotypes. IL-33 mRNA is rapidly regulated, but the fate of synthesized IL-33 protein is unknown. To understand the interplay among IL-33, IFN-γ, and IL-4 proteins, recombinant replication-deficient adenoviruses were produced an...

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Détails bibliographiques
Auteurs principaux: Kopach, Pavel, Lockatell, Virginia, Pickering, Edward M., Haskell, Ronald E., Anderson, Richard D., Hasday, Jeffrey D., Todd, Nevins W., Luzina, Irina G., Atamas, Sergei P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002090/
https://ncbi.nlm.nih.gov/pubmed/24619410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534396
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