FULL-LENGTH INTERLEUKIN-33 PROMOTES INFLAMMATION BUT NOT TH2 RESPONSE IN VIVO IN AN ST2-INDEPENDENT FASHION

Expression of IL-33 is elevated in patients with pulmonary diseases, and full-length (not proteolytically processed) IL-33 is the predominant form in the lungs in health and disease. To determine whether activation of IL-33 is needed for functional effects, activities of full-length mouse (flm) and...

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Main Authors: Luzina, Irina G., Pickering, Edward M., Kopach, Pavel, Kang, Phillip H., Lockatell, Virginia, Todd, Nevins W., Papadimitriou, John C., McKenzie, Andrew N. J., Atamas, Sergei P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381874/
https://ncbi.nlm.nih.gov/pubmed/22634619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200259
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