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Splice isoforms of human interleukin-4 are functionally active in mice in vivo

Interleukin-4 (IL-4) acts on cultured cells in a species-specific fashion, although several reports have suggested that human (h) IL-4 may be functionally active in rodents in vivo. The latter finding, if true, would not only offer possibilities for pre-clinical testing of novel hIL-4-targeting ther...

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Détails bibliographiques
Auteurs principaux: Luzina, Irina G, Lockatell, Virginia, Todd, Nevins W, Keegan, Achsah D, Hasday, Jeffrey D, Atamas, Sergei P
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044904/
https://ncbi.nlm.nih.gov/pubmed/21219317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03393.x
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