Natural Production and Functional Effects of Alternatively Spliced Interleukin-4 Protein in Asthma

We have previously described an alternatively spliced isoform of IL-4 mRNA that omits exon 2 and is termed IL-4δ2. However, the natural production of IL-4δ2 protein and its association with disease have not been previously assessed due to unavailability of an antibody that interacts with IL-4δ2 with...

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Bibliographic Details
Main Authors: Luzina, Irina G., Lockatell, Virginia, Lavania, Sachin, Pickering, Edward M., Kang, Phillip H., Bashkatova, Yulia N., Andreev, Sergey M., Atamas, Sergei P.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290677/
https://ncbi.nlm.nih.gov/pubmed/22249152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2011.12.017
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