טוען...
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF
Histone methyltransferase MLL4 is centrally involved in transcriptional regulation and is often mutated in human diseases, including cancer and developmental disorders. MLL4 contains a catalytic SET domain that mono-methylates histone H3K4 and seven PHD fingers of unclear function. Here, we identify...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534582/ https://ncbi.nlm.nih.gov/pubmed/31127101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10324-8 |
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