Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription

The MLL (Mixed Lineage Leukemia) proto-oncogene encodes a histone methyltransferase that creates the methylated histone H3K4 epigenetic marks, commonly associated with actively transcribed genes. In addition to its canonical histone methyltransferase SET domain, the MLL protein contains three plant...

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Bibliografiset tiedot
Päätekijät: Chang, Pei-Yun, Hom, Robert A., Musselman, Catherine A., Zhu, Li, Kuo, Alex, Gozani, Or, Kutateladze, Tatiana G., Cleary, Michael L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886590/
https://ncbi.nlm.nih.gov/pubmed/20452361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.05.005
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