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Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription
The MLL (Mixed Lineage Leukemia) proto-oncogene encodes a histone methyltransferase that creates the methylated histone H3K4 epigenetic marks, commonly associated with actively transcribed genes. In addition to its canonical histone methyltransferase SET domain, the MLL protein contains three plant...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886590/ https://ncbi.nlm.nih.gov/pubmed/20452361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.05.005 |
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