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Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells

Biliary esophageal reflux at acidic pH is considered a risk factor in laryngopharyngeal cancer. We previously showed the key role NF-κB in mediating acidic bile-induced pre-neoplastic events in hypopharyngeal cells, and that co-administration of specific NF-κB inhibitor, BAY 11-7082, together with a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Doukas, Panagiotis G., Vageli, Dimitra P., Doukas, Sotirios G., Sasaki, Clarence T.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534360/
https://ncbi.nlm.nih.gov/pubmed/31164956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26917
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