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Curcumin prevents the bile reflux‐induced NF‐κB‐related mRNA oncogenic phenotype, in human hypopharyngeal cells

The presence of bile is not an uncommon finding in acidic oesophageal and extra‐oesophageal refluxate, possibly affecting the hypopharyngeal mucosa and leading to neoplastic events. We recently demonstrated that acidic bile (pH ≤ 4.0) can induce NF‐κB activation and oncogenic mRNA phenotype in norma...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Vageli, Dimitra P., Doukas, Sotirios G., Spock, Todd, Sasaki, Clarence T.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111812/
https://ncbi.nlm.nih.gov/pubmed/29911313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13701
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