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Curcumin prevents the bile reflux‐induced NF‐κB‐related mRNA oncogenic phenotype, in human hypopharyngeal cells

The presence of bile is not an uncommon finding in acidic oesophageal and extra‐oesophageal refluxate, possibly affecting the hypopharyngeal mucosa and leading to neoplastic events. We recently demonstrated that acidic bile (pH ≤ 4.0) can induce NF‐κB activation and oncogenic mRNA phenotype in norma...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Vageli, Dimitra P., Doukas, Sotirios G., Spock, Todd, Sasaki, Clarence T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111812/
https://ncbi.nlm.nih.gov/pubmed/29911313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13701
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