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In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile–Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa()()

PURPOSE: Bile-containing gastroesophageal reflux may promote cancer at extraesophageal sites. Acidic bile can accelerate NF-κB activation and molecular events, linked to premalignant changes in murine hypopharyngeal mucosa (HM). We hypothesize that short-term in vivo topical application of NF-κB inh...

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Detaylı Bibliyografya
Yayımlandı:Neoplasia
Asıl Yazarlar: Sasaki, Clarence T., Doukas, Sotirios G., Vageli, Dimitra P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909679/
https://ncbi.nlm.nih.gov/pubmed/29529473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.02.001
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