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NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells

We previously demonstrated that acidic bile activates NF‐κB, deregulating the expression of oncogenic miRNA markers, in pre‐malignant murine laryngopharyngeal mucosa. Here, we hypothesize that the in vitro exposure of human hypopharyngeal cells to acidic bile deregulates cancer‐related miRNA markers...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Doukas, Sotirios G., Vageli, Dimitra P., Sasaki, Clarence T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908126/
https://ncbi.nlm.nih.gov/pubmed/29516639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13591
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