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NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells

We previously demonstrated that acidic bile activates NF‐κB, deregulating the expression of oncogenic miRNA markers, in pre‐malignant murine laryngopharyngeal mucosa. Here, we hypothesize that the in vitro exposure of human hypopharyngeal cells to acidic bile deregulates cancer‐related miRNA markers...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Doukas, Sotirios G., Vageli, Dimitra P., Sasaki, Clarence T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908126/
https://ncbi.nlm.nih.gov/pubmed/29516639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13591
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