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The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights

Cancers of the laryngopharynx represent the most devastating of the head and neck malignancies and additional risk factors are now epidemiologically linked to this disease. Using an in vivo model (Mus musculus C57Bl/6J), we provide novel evidence that acidic bile (pH 3.0) progressively promotes inva...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sasaki, Clarence T., Doukas, Sotirios G., Costa, Jose, Vageli, Dimitra P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281001/
https://ncbi.nlm.nih.gov/pubmed/32344873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051064
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