Curcumin induces apoptosis in JAK2‐mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways

Myeloproliferative neoplasms are chronic myeloid cancers divided in Philadelphia positive and negative. The JAK2 V617F is the most common mutation in Philadelphia negative patients and results in a constitutive activation of the JAK/STAT pathway, conferring a proliferative advantage and apoptosis in...

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Опубликовано в: :J Cell Mol Med
Главные авторы: Petiti, Jessica, Rosso, Valentina, Lo Iacono, Marco, Panuzzo, Cristina, Calabrese, Chiara, Signorino, Elisabetta, Pironi, Lucrezia, Cartellà, Antonio, Bracco, Enrico, Pergolizzi, Barbara, Beltramo, Tiziana, Fava, Carmen, Cilloni, Daniela
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533565/
https://ncbi.nlm.nih.gov/pubmed/31033209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14326
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