Curcumin induces apoptosis in JAK2‐mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways

Myeloproliferative neoplasms are chronic myeloid cancers divided in Philadelphia positive and negative. The JAK2 V617F is the most common mutation in Philadelphia negative patients and results in a constitutive activation of the JAK/STAT pathway, conferring a proliferative advantage and apoptosis in...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Petiti, Jessica, Rosso, Valentina, Lo Iacono, Marco, Panuzzo, Cristina, Calabrese, Chiara, Signorino, Elisabetta, Pironi, Lucrezia, Cartellà, Antonio, Bracco, Enrico, Pergolizzi, Barbara, Beltramo, Tiziana, Fava, Carmen, Cilloni, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533565/
https://ncbi.nlm.nih.gov/pubmed/31033209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14326
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