Curcumin induces apoptosis in JAK2‐mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways

Myeloproliferative neoplasms are chronic myeloid cancers divided in Philadelphia positive and negative. The JAK2 V617F is the most common mutation in Philadelphia negative patients and results in a constitutive activation of the JAK/STAT pathway, conferring a proliferative advantage and apoptosis in...

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Bibliografski detalji
Izdano u:J Cell Mol Med
Glavni autori: Petiti, Jessica, Rosso, Valentina, Lo Iacono, Marco, Panuzzo, Cristina, Calabrese, Chiara, Signorino, Elisabetta, Pironi, Lucrezia, Cartellà, Antonio, Bracco, Enrico, Pergolizzi, Barbara, Beltramo, Tiziana, Fava, Carmen, Cilloni, Daniela
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533565/
https://ncbi.nlm.nih.gov/pubmed/31033209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14326
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