Evaluation of Pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [(18)F]FP-DTBZ in Healthy Subjects and Patients with Type 1 Diabetes

PURPOSE: Previous studies demonstrated the utility of [(18)F]fluoropropyl-(+)-dihydrotetrabenazine ([(18)F]FP-(+)-DTBZ) as a positron emission tomography (PET) radiotracer for the vesicular monoamine transporter type 2 (VMAT2) to quantify beta cell mass in healthy control (HC) and type 1 diabetes me...

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Vydáno v:Mol Imaging Biol
Hlavní autoři: Naganawa, Mika, Lim, Keunpoong, Nabulsi, Nabeel B., Lin, Shu-fei, Labaree, David, Ropchan, Jim, Herold, Kevan C., Huang, Yiyun, Harris, Paul, Ichise, Masanori, Cline, Gary W., Carson, Richard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533199/
https://ncbi.nlm.nih.gov/pubmed/29468404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-018-1170-6
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