Evaluation of PET Brain Radioligands for Imaging Pancreatic β-Cell Mass: Potential Utility of (11)C-(+)-PHNO

Type 1 diabetes mellitus (T1DM) is characterized by a loss of β-cells in the islets of Langerhans of the pancreas and subsequent deficient insulin secretion in response to hyperglycemia. Development of an in vivo test to measure β-cell mass (BCM) would greatly enhance the ability to track diabetes t...

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Bibliographic Details
Published in:J Nucl Med
Main Authors: Bini, Jason, Naganawa, Mika, Nabulsi, Nabeel, Huang, Yiyun, Ropchan, Jim, Lim, Keunpoong, Najafzadeh, Soheila, Herold, Kevan C., Cline, Gary W., Carson, Richard E.
Format: Artigo
Language:Inglês
Published: Society of Nuclear Medicine 2018
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071501/
https://ncbi.nlm.nih.gov/pubmed/29371405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.197285
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