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PET quantification of pancreatic VMAT 2 binding using (+) and (−) enantiomers of [(18)F]FP-DTBZ in baboons
OBJECTIVES: The exact cause(s) of apparent overestimation of β cell mass (BCM) with vesicular monoamine transporter type 2 (VMAT2) PET imaging in type 1 diabetes (T1D) is unknown. The objectives were to estimate in baboons non-displaceable binding of [(18)F]fluoropropyl (FP)-(+)- dihydrotetrabenazin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514630/ https://ncbi.nlm.nih.gov/pubmed/23102539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.09.003 |
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