Cross-sectional and Test-Retest Characterization of PET with [(18)F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes

PURPOSE: The vesicular monoamine transporter, type 2 (VMAT2) is expressed by insulin producing β cells and was evaluated as a biomarker of β cell mass (BCM) by positron emission tomography (PET) with [(18)F]fluoropropyl-dihydrotetrabenazine ([(18)F]FP-(+)-DTBZ). PROCEDURES: We evaluated the feasibil...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Freeby, Matthew J., Kringas, Patricia, Goland, Robin S., Leibel, Rudolph L., Maffei, Antonella, Divgi, Chaitan, Ichise, Masanori, Harris, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783444/
https://ncbi.nlm.nih.gov/pubmed/26370678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-015-0888-7
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