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(11)C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls

Type 2 vesicular monoamine transporter (VMAT2), found in the brain, is also expressed by β-cells of the pancreas in association with insulin. Preclinical experiments suggested that (11)C-dihydrotetrabenazine PET–measured VMAT2 binding might serve as a biomarker of β-cell mass. We evaluated the feasi...

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Detalhes bibliográficos
Main Authors: Goland, Robin, Freeby, Matthew, Parsey, Ramin, Saisho, Yoshifumi, Kumar, Dileep, Simpson, Norman, Hirsch, Joy, Prince, Martin, Maffei, Antonella, Mann, J. John, Butler, Peter C., Van Heertum, Ronald, Leibel, Rudolph L., Ichise, Masanori, Harris, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629294/
https://ncbi.nlm.nih.gov/pubmed/19223416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.054866
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