Longitudinal noninvasive PET-based β cell mass estimates in a spontaneous diabetes rat model

Diabetes results from an absolute or relative reduction in pancreatic β cell mass (BCM) leading to insufficient insulin secretion and hyperglycemia. Measurement of insulin secretory capacity is currently used as a surrogate measure of BCM. However, serum insulin concentrations provide an imprecise i...

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Main Authors: Souza, Fabiola, Simpson, Norman, Raffo, Anthony, Saxena, Chitra, Maffei, Antonella, Hardy, Mark, Kilbourn, Michael, Goland, Robin, Leibel, Rudolph, Mann, J. John, Van Heertum, Ronald, Harris, Paul E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462946/
https://ncbi.nlm.nih.gov/pubmed/16710474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27645
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