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Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine

Despite different embryological origins, islet beta-cells and neurons share expression of many genes and display multiple functional similarities. One shared gene product, VMAT2, vesicular monoamine transporter type 2 (also known as SLC18A2), is highly expressed in human beta-cells relative to other...

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Main Authors: Raffo, Anthony, Hancock, Kolbe, Polito, Teresa, Andan, Gordon, Witkowski, Piotr, Hardy, Mark, Barba, Pasquale, Ferrara, Caterina, Maffei, Antonella, Freeby, Matthew, Goland, Robin, Leibel, Rudolph L., Sweet, Ian, Harris, Paul E.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712213/
https://ncbi.nlm.nih.gov/pubmed/18577569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-07-0632
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