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Effect of Histone Lysine Methylation on DNA Lesion Reactivity in Nucleosome Core Particles
Lysine methylation is a common posttranslational histone modification that regulates transcription and gene expression. The lysine residues in the histone tail also react with damaged nucleotides in chromatin, including abasic sites and N7-methyl-2'-deoxyguanosine, the major product of DNA meth...
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| Veröffentlicht in: | Chem Res Toxicol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533150/ https://ncbi.nlm.nih.gov/pubmed/30916939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00049 |
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