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Effect of Histone Lysine Methylation on DNA Lesion Reactivity in Nucleosome Core Particles

Lysine methylation is a common posttranslational histone modification that regulates transcription and gene expression. The lysine residues in the histone tail also react with damaged nucleotides in chromatin, including abasic sites and N7-methyl-2'-deoxyguanosine, the major product of DNA meth...

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Bibliografiset tiedot
Julkaisussa:Chem Res Toxicol
Päätekijät: Yang, Kun, Prasse, Carsten, Greenberg, Marc M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533150/
https://ncbi.nlm.nih.gov/pubmed/30916939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00049
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