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The polyploid state restricts hepatocyte proliferation and liver regeneration
The liver contains a mixture of hepatocytes with diploid or polyploid (tetraploid, octaploid, etc.) nuclear content. Polyploid hepatocytes are commonly found in adult mammals, representing ~90% of the entire hepatic pool in rodents. The cellular and molecular mechanisms that regulate polyploidizatio...
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| Publicat a: | Hepatology |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6532408/ https://ncbi.nlm.nih.gov/pubmed/30244478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30286 |
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