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The polyploid state restricts hepatocyte proliferation and liver regeneration

The liver contains a mixture of hepatocytes with diploid or polyploid (tetraploid, octaploid, etc.) nuclear content. Polyploid hepatocytes are commonly found in adult mammals, representing ~90% of the entire hepatic pool in rodents. The cellular and molecular mechanisms that regulate polyploidizatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hepatology
Egile Nagusiak: Wilkinson, Patrick D., Delgado, Evan R., Alencastro, Frances, Leek, Madeleine P., Roy, Nairita, Weirich, Matthew P., Stahl, Elizabeth C., Otero, P. Anthony, Chen, Maelee I., Brown, Whitney K., Duncan, Andrew W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532408/
https://ncbi.nlm.nih.gov/pubmed/30244478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30286
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