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Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains
The cytoplasmic accumulation of the nuclear TAR DNA-binding protein 43 (TDP-43) is a pathologic hallmark in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and other neurological disorders. However, most transgenic TDP-43 rodent models show predominant nuclear distribution of TDP-4...
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| Publicado no: | Acta Neuropathol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6531422/ https://ncbi.nlm.nih.gov/pubmed/30810811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-01979-0 |
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