cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

The ability of cytosolic lipopolysaccharide (LPS) to activate caspase-11–dependent nonclassical inflammasome is intricately controlled to avoid excessive inflammatory responses. However, very little is known about the regulatory role of various metabolic pathways in the control of caspase-11 activat...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Chen, Ruochan, Zeng, Ling, Zhu, Shan, Liu, Jiao, Zeh, Herbert J., Kroemer, Guido, Wang, Haichao, Billiar, Timothy R., Jiang, Jianxin, Tang, Daolin, Kang, Rui
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531004/
https://ncbi.nlm.nih.gov/pubmed/31131320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav5562
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