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TMEM173 Drives Lethal Coagulation in Sepsis

The discovery of TMEM173/STING-dependent innate immunity has recently provided guidance for the prevention and management of inflammatory disorders. Here, we show that myeloid TMEM173 occupies an essential role in regulating coagulation in bacterial infections through a mechanism independent of type...

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Bibliographic Details
Published in:Cell Host Microbe
Main Authors: Zhang, Hui, Zeng, Ling, Xie, Min, Liu, Jiao, Zhou, Borong, Wu, Runliu, Cao, Lizhi, Kroemer, Guido, Wang, Haichao, Billiar, Timothy R., Zeh, Herbert J., Kang, Rui, Jiang, Jianxin, Yu, Yan, Tang, Daolin
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316085/
https://ncbi.nlm.nih.gov/pubmed/32142632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.02.004
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