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Computational design of structured loops for new protein functions

The ability to engineer the precise geometries, fine-tuned energetics, and subtle dynamics that are characteristic of functional proteins is a major unsolved challenge in the field of computational protein design. In natural proteins, functional sites exhibiting these properties often feature struct...

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Détails bibliographiques
Publié dans:Biol Chem
Auteurs principaux: Kundert, Kale, Kortemme, Tanja
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530579/
https://ncbi.nlm.nih.gov/pubmed/30676995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2018-0348
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