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Computational Protein Design Quantifies Structural Constraints on Amino Acid Covariation
Amino acid covariation, where the identities of amino acids at different sequence positions are correlated, is a hallmark of naturally occurring proteins. This covariation can arise from multiple factors, including selective pressures for maintaining protein structure, requirements imposed by a spec...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828131/ https://ncbi.nlm.nih.gov/pubmed/24244128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003313 |
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