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Methods in Enzymology: “Flexible backbone sampling methods to model and design protein alternative conformations”

Sampling alternative conformations is key to understanding how proteins work and engineering them for new functions. However, accurately characterizing and modeling protein conformational ensembles remains experimentally and computationally challenging. These challenges must be met before protein co...

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Detalles Bibliográficos
Main Authors: Ollikainen, Noah, Smith, Colin A., Fraser, James S., Kortemme, Tanja
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750959/
https://ncbi.nlm.nih.gov/pubmed/23422426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394292-0.00004-7
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