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Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design
Predicting the set of sequences that are tolerated by a protein or protein interface, while maintaining a desired function, is useful for characterizing protein interaction specificity and for computationally designing sequence libraries to engineer proteins with new functions. Here we provide a gen...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138746/ https://ncbi.nlm.nih.gov/pubmed/21789164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020451 |
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