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Comparison of Rosetta flexible-backbone computational protein design methods on binding interactions

Computational design of binding sites in proteins remains difficult, in part due to limitations in our current ability to sample backbone conformations that enable precise and accurate geometric positioning of side chains during sequence design. Here we present a benchmark framework for comparison b...

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Bibliografische gegevens
Gepubliceerd in:Proteins
Hoofdauteurs: Loshbaugh, Amanda L., Kortemme, Tanja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901717/
https://ncbi.nlm.nih.gov/pubmed/31344278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25790
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