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Retinol-Binding Protein Interferes with Transthyretin-Mediated β-Amyloid Aggregation Inhibition
β-Amyloid (Aβ) aggregation is causally linked to Alzheimer’s disease. On the basis of in vitro and transgenic animal studies, transthyretin (TTR) is hypothesized to provide neuroprotection against Aβ toxicity by binding to Aβ and inhibiting its aggregation. TTR is a homotetrameric protein that circu...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6530574/ https://ncbi.nlm.nih.gov/pubmed/30024734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00517 |
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