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A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin

Self-association of β-amyloid (Aβ) into oligomers and fibrils is associated with Alzheimer’s disease (AD), motivating the search for compounds that bind to and inhibit Aβ oligomerization and/or neurotoxicity. Peptides are an attractive class of such compounds, with potential advantages over small mo...

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Bibliografske podrobnosti
izdano v:ACS Chem Neurosci
Main Authors: Cho, Patricia Y., Joshi, Gururaj, Boersma, Melissa D., Johnson, Jeffrey A., Murphy, Regina M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797071/
https://ncbi.nlm.nih.gov/pubmed/25713928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500272a
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