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Transthyretin as both Sensor and Scavenger of Aβ Oligomers
Transthyretin (TTR) is a homotetrameric transport protein, assembled from monomers that each contains two four-stranded β-sheets and a short α-helix and loop. In the tetramer, the ‘inner’ β-sheet forms a hydrophobic pocket while the helix and loop are solvent-exposed. Beta-amyloid (Aβ) aggregates bi...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658121/ https://ncbi.nlm.nih.gov/pubmed/23570378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4001613 |
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