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Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level
Interleukin (IL)‐18, formerly known as interferon (IFN)‐γ‐inducing factor, is a crucial mediator of host defence and inflammation. Control of IL‐18 bioactivity by its endogenous antagonist IL‐18 binding protein (IL‐18BP) is a major objective of immunoregulation. IL‐18BP is strongly up‐regulated by I...
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| Publicado en: | J Cell Mol Med |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Publishing Ltd
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6529978/ https://ncbi.nlm.nih.gov/pubmed/19046253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00604.x |
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