Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA

U1-snRNA is an integral part of the U1 ribonucleoprotein pivotal for pre-mRNA splicing. Toll-like receptor (TLR) signaling has recently been associated with immunoregulatory capacities of U1-snRNA. Using lung A549 epithelial/carcinoma cells, we report for the first time on interferon regulatory fact...

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Bibliographische Detailangaben
Hauptverfasser: Sadik, Christian D., Bachmann, Malte, Pfeilschifter, Josef, Mühl, Heiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731906/
https://ncbi.nlm.nih.gov/pubmed/19541850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp525
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