The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells

1. The protease inhibitor ritonavir is an integral part of current antiretroviral therapy targeting human immunodeficiency virus. Recent studies demonstrate that ritonavir induces apoptotic cell death with high efficiency in lymphoblastoid cell lines. Moreover, ritonavir can suppress activation of t...

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Hlavní autoři: Mühl, Heiko, Paulukat, Jens, Höfler, Sonja, Hellmuth, Markus, Franzen, Rochus, Pfeilschifter, Josef
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575947/
https://ncbi.nlm.nih.gov/pubmed/15504750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706023
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