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Curved microstructures promote osteogenesis of mesenchymal stem cells via the RhoA/ROCK pathway

OBJECTIVES: Cells in the osteon reside in a curved space, accordingly, the curvature of the microenvironment is an important geometric feature in bone formation. However, it is not clear how curved microstructures affect cellular behaviour in bone tissue. MATERIALS AND METHODS: Rat primary bone marr...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Zhang, Qi, Lin, Shiyu, Zhang, Tao, Tian, Taoran, Ma, Quanquan, Xie, Xueping, Xue, Changyue, Lin, Yunfeng, Zhu, Bofeng, Cai, Xiaoxiao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529063/
https://ncbi.nlm.nih.gov/pubmed/28714177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12356
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