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Curved microstructures promote osteogenesis of mesenchymal stem cells via the RhoA/ROCK pathway

OBJECTIVES: Cells in the osteon reside in a curved space, accordingly, the curvature of the microenvironment is an important geometric feature in bone formation. However, it is not clear how curved microstructures affect cellular behaviour in bone tissue. MATERIALS AND METHODS: Rat primary bone marr...

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Bibliografiske detaljer
Udgivet i:Cell Prolif
Main Authors: Zhang, Qi, Lin, Shiyu, Zhang, Tao, Tian, Taoran, Ma, Quanquan, Xie, Xueping, Xue, Changyue, Lin, Yunfeng, Zhu, Bofeng, Cai, Xiaoxiao
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529063/
https://ncbi.nlm.nih.gov/pubmed/28714177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12356
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