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Elevated BMP and mechanical signaling through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by the formation of extra-skeletal bone, or heterotopic ossification (HO), in soft connective tissues such as skeletal muscle. All familial and sporadic cases with a classic clinical presentation of FOP carry a gain-...
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| Publicado no: | J Bone Miner Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7209824/ https://ncbi.nlm.nih.gov/pubmed/31107558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3760 |
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