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ACVR1(R206H) FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification
An activating bone morphogenetic proteins (BMP) type I receptor ACVR1 (ACVR1(R206H)) mutation enhances BMP pathway signaling and causes the rare genetic disorder of heterotopic (extraskeletal) bone formation fibrodysplasia ossificans progressiva. Heterotopic ossification frequently occurs following...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6337906/ https://ncbi.nlm.nih.gov/pubmed/30379592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-05-0311 |
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