Dysregulated BMP Signaling and Enhanced Osteogenic Differentiation of Connective Tissue Progenitor Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP)

The study of FOP, a disabling genetic disorder of progressive heterotopic ossification, is hampered by the lack of readily available connective tissue progenitor cells. We isolated such cells from discarded primary teeth of patients with FOP and controls and discovered dysregulation of BMP signaling...

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Detalhes bibliográficos
Main Authors: Billings, Paul C, Fiori, Jennifer L, Bentwood, Jennifer L, O'Connell, Michael P, Jiao, Xiangyang, Nussbaum, Burton, Caron, Robert J, Shore, Eileen M, Kaplan, Frederick S
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669159/
https://ncbi.nlm.nih.gov/pubmed/17967130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.071030
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