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ECM Compliance Regulates Osteogenesis by Influencing MAPK Signaling Downstream of RhoA and ROCK

The compliance of the extracellular matrix (ECM) regulates osteogenic differentiation by modulating extracellular signal-regulated kinase (ERK) activity. However, the molecular mechanism linking ECM compliance to the ERK-mitogen-activated protein kinase (MAPK) pathway remains unclear. Furthermore, R...

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Detalhes bibliográficos
Main Authors: Khatiwala, Chirag B., Kim, Peter D., Peyton, Shelly R., Putnam, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672206/
https://ncbi.nlm.nih.gov/pubmed/19113908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.081240
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