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Curved microstructures promote osteogenesis of mesenchymal stem cells via the RhoA/ROCK pathway

OBJECTIVES: Cells in the osteon reside in a curved space, accordingly, the curvature of the microenvironment is an important geometric feature in bone formation. However, it is not clear how curved microstructures affect cellular behaviour in bone tissue. MATERIALS AND METHODS: Rat primary bone marr...

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Vydáno v:Cell Prolif
Hlavní autoři: Zhang, Qi, Lin, Shiyu, Zhang, Tao, Tian, Taoran, Ma, Quanquan, Xie, Xueping, Xue, Changyue, Lin, Yunfeng, Zhu, Bofeng, Cai, Xiaoxiao
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529063/
https://ncbi.nlm.nih.gov/pubmed/28714177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12356
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