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DeTiN : Overcoming Tumor in Normal Contamination
A key step in achieving accurate detection of somatic mutations is comparison of sequencing data from a tumor sample to its matched germline control. Sensitivity to detect somatic variants is greatly reduced when the matched normal sample is contaminated with tumor cells. To overcome this limitation...
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| Vydáno v: | Nat Methods |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528031/ https://ncbi.nlm.nih.gov/pubmed/29941871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0036-9 |
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