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ContEst: estimating cross-contamination of human samples in next-generation sequencing data

Summary: Here, we present ContEst, a tool for estimating the level of cross-individual contamination in next-generation sequencing data. We demonstrate the accuracy of ContEst across a range of contamination levels, sources and read depths using sequencing data mixed in silico at known concentration...

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Bibliografiska uppgifter
Huvudupphovsmän: Cibulskis, Kristian, McKenna, Aaron, Fennell, Tim, Banks, Eric, DePristo, Mark, Getz, Gad
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167057/
https://ncbi.nlm.nih.gov/pubmed/21803805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr446
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