The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are already revolutionizing our understanding of genetic variation among individuals. However, the massive data sets generated by NGS—the 1000 Genome pilot alone includes nearly five terabases—make writing feature-rich,...

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Detalhes bibliográficos
Main Authors: McKenna, Aaron, Hanna, Matthew, Banks, Eric, Sivachenko, Andrey, Cibulskis, Kristian, Kernytsky, Andrew, Garimella, Kiran, Altshuler, David, Gabriel, Stacey, Daly, Mark, DePristo, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928508/
https://ncbi.nlm.nih.gov/pubmed/20644199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.107524.110
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