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PurityEst: estimating purity of human tumor samples using next-generation sequencing data
Summary: We developed a novel algorithm, PurityEst, to infer the tumor purity level from the allelic differential representation of heterozygous loci with somatic mutations in a human tumor sample with a matched normal tissue using next-generation sequencing data. We applied our tool to a whole canc...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426843/ https://ncbi.nlm.nih.gov/pubmed/22743227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts365 |
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