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Optimal conditions for lentiviral transduction of engrafting human CD34(+) cells

Cytokines are required for γ-retroviral transduction of human CD34(+) cells. However, cytokines may reduce engraftment of CD34(+) cells and may not be necessary for their lentiviral transduction. We sought to optimize transduction and engraftment of human CD34(+) cells using lentiviral vectors. Sing...

詳細記述

保存先:
書誌詳細
出版年:Gene Ther
主要な著者: Uchida, N, Hsieh, MM, Hayakawa, J, Madison, C, Washington, KN, Tisdale, JF
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525965/
https://ncbi.nlm.nih.gov/pubmed/21544097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.63
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